Can computer simulations replace human trials? This episode explores a rigorous framework for in silico clinical trials that establishes credibility through verification, validation, and uncertainty quantification. Unlike Bayesian approaches, this method uses a build-validate-predict structure to address uncertainties. Our neuromodulation device case study demonstrates how validated models could transform medical device testing—reducing costs and ethical concerns while maintaining scientific integrity.

Folgen-ID: 1000703416728

GUID: insilicouk.podbean.com/9f1eff24-8df7-3d28-90c8-8c248f241548

Erscheinungs­datum: 14.4.2025, 07:00:00